Symbol
Name
ID

Ctsl
cathepsin L
MGI:88564

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal thymus morphology

abnormal thymus lobule morphology

enlarged thymus cortex

abnormal thymus corticomedullary boundary morphology

thymus atrophy

abnormal T cell differentiation

abnormal CD4-positive T cell differentiation

abnormal CD8-positive, alpha-beta T cell differentiation

abnormal leukocyte cell number

increased central memory CD4-positive, alpha-beta T cell number

increased effector memory CD4-positive, alpha-beta T cell number

decreased CD4-positive, alpha-beta T cell number

increased central memory CD8 positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

decreased alpha-beta T cell number

increased alpha-beta T cell number

increased regulatory T cell number

decreased osteoclast cell number

abnormal CD8-positive, alpha beta T cell morphology

abnormal osteoclast physiology

Availability

Mouse Genotype

Ctsl^m1Btlr/Ctsl^m1Btlr

Ctsl^nkt/Ctsl^nkt

Ctsl^tm1.2Thre/Ctsl^tm1.2Thre

Ctsl^tm1Alpk/Ctsl^tm1Alpk

Ctsl^tm1Cptr/Ctsl^tm1Cptr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23